Non-local metasurfaces for spectrally decoupled wavefront manipulation and eye tracking.

Metasurface-based optical elements typically manipulate light waves by imparting space-variant changes in the amplitude and phase with a dense array of scattering nanostructures. The highly localized and low optical-quality-factor (Q) modes of nanostructures are beneficial for wavefront shaping as they afford quasi-local control over the electromagnetic fields. However, many emerging imaging, sensing, communication, display and nonlinear optics applications instead require flat, high-Q optical elements that provide substantial energy storage and a much higher degree of spectral control over the wavefront. Here, we demonstrate high-Q, non-local metasurfaces with atomically thin metasurface elements that offer notably enhanced light-matter interaction and fully decoupled optical functions at different wavelengths. We illustrate a possible use of such a flat optic in eye tracking for eyewear. Here, a metasurface patterned on a regular pair of eye glasses provides an unperturbed view of the world across the visible spectrum and redirects near-infrared light to a camera to allow imaging of the eye.

Hypothesis of macroscopic quantum state in biological systems and discussion on the possibility of its experimental verification.

Earlier it was noted that the functioning of biological systems is accompanied by a very low level of energy dissipation, and it was assumed that a physical mechanism similar to that which works in superconductivity can operate here. The paper proposes a hypothesis that the phenomenon of life is not based on superconductivity, but on some so far unexplored macroscopic quantum state of organic structures making up the cell. It is assumed that this state is also characterized by the presence of an energy gap in the electronic spectrum, which makes the state stable and provides a low level of energy dissipation. The possibility of using optical spectroscopy methods for identifying the energy gap in biological objects is analyzed. It is assumed that the virus is alive inside the host cell, but not alive outside the host cell. It is proposed to use Raman spectroscopy of the process of bacterial infection with phages to search for the energy gap. This should confirm or refute the main hypothesis, as well as provide an opportunity to answer the question: "Are viruses alive?"

Portable device for presbyopia correction with optoelectronic lenses driven by pupil response.

A novel portable device has been developed and built to dynamically, and automatically, correct presbyopia by means of a couple of opto-electronics lenses driven by pupil tracking. The system is completely portable providing with a high range of defocus correction up to 10 D. The glasses are controlled and powered by a smartphone. To achieve a truly real-time response, image processing algorithms have been implemented in OpenCL and ran on the GPU of the smartphone. To validate the system, different visual experiments were carried out in presbyopic subjects. Visual acuity was maintained nearly constant for a range of distances from 5 m to 20 cm.

Microscopic sensors using optical wireless integrated circuits.

We present a platform for parallel production of standalone, untethered electronic sensors that are truly microscopic, i.e., smaller than the resolution of the naked eye. This platform heterogeneously integrates silicon electronics and inorganic microlight emitting diodes (LEDs) into a 100-µm-scale package that is powered by and communicates with light. The devices are fabricated, packaged, and released in parallel using photolithographic techniques, resulting in ∼10,000 individual sensors per square inch. To illustrate their use, we show proof-of-concept measurements recording voltage, temperature, pressure, and conductivity in a variety of environments.

Label-free whole-colony imaging and metabolic analysis of metastatic pancreatic cancer by an autoregulating flexible optical system.

Cancer metastasis is a Gordian knot for tumor diagnosis and therapy. Many studies have demonstrated that metastatic processes are inevitably affected by the tumor microenvironment. Histopathology is used universally as the gold standard for cancer diagnosis despite the lengthy preparation process and invasiveness. Methods: Here, we introduced a supercontinuum and super-wide-tuning integrated multimodal platform, which combines the confocal, nonlinear and fluorescence lifetime microscopy with autoregulations, for label-free evaluation of fresh tissue and pathological sections. Based on various automated tunable lasers, synchronized and self-adjusting components and eight fast switching detection channels, the system features fast, large-field and subcellular-scale imaging of exogenous and endogenous fluorophores, nonlinear coherent scattering and lifetime contrast. Results: With such an integrated multi-dimensional system, we searched the metastatic region by two-photon and three-photon excited autofluorescence, analyzed the cancer invasion by second harmonic generation and revealed the affected cellular metabolism by phasor-lifetime. We demonstrated the flexible measurement of multiple nonlinear modalities at NIR I and II excitation with a pre-compensation for group delay dispersion of ~7,000 fs2 and low power of <40 mW, and of dual autofluorescence lifetime decays for phasor approach to decompose cancer-associated and disassociated components. This significantly revealed the metastatic and metabolic optical signatures of the whole colony of pancreatic cancers. Conclusion: The synergistic effect of the system demonstrates the great potential to translate this technique into routine clinical applications, particularly for large-scale and quantitative studies of metastatic colonization.

On the power profiles of contact lenses measured with NIMO TR1504 / Perfiles de potencia de las lentes de contacto medidas con NIMO TR1504

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Improvement of the chromatic dispersion tolerance in coherent optical OFDM systems using shifted DFT windows for ultra-long-haul optical transmission systems.

In a high-capacity ultra-long-haul optical coherent orthogonal frequency-division multiplexing (CO-OFDM) system, the dispersion tolerance is determined by the length of cyclic extension (CE). In this paper, we propose a novel scheme to substantially improve the dispersion tolerance of CO-OFDM systems without increasing the CE length. Multiple time-shifted discrete Fourier transform (DFT) windows are exploited at the receiver, each demodulating only a part of the subcarriers. Effectively, the proposed scheme reduces the bandwidth of the OFDM signals under demodulation. Numerical simulations are performed to show the improved dispersion tolerance of the proposed scheme in comparison with the conventional CO-OFDM system. We show that the dispersion tolerance improves by a factor equal to the number of DFT windows. The tradeoff between the improved dispersion tolerance and increased receiver complexity is also presented.

Robust range estimation with a monocular camera for vision-based forward collision warning system.

We propose a range estimation method for vision-based forward collision warning systems with a monocular camera. To solve the problem of variation of camera pitch angle due to vehicle motion and road inclination, the proposed method estimates virtual horizon from size and position of vehicles in captured image at run-time. The proposed method provides robust results even when road inclination varies continuously on hilly roads or lane markings are not seen on crowded roads. For experiments, a vision-based forward collision warning system has been implemented and the proposed method is evaluated with video clips recorded in highway and urban traffic environments. Virtual horizons estimated by the proposed method are compared with horizons manually identified, and estimated ranges are compared with measured ranges. Experimental results confirm that the proposed method provides robust results both in highway and in urban traffic environments.

Optical materials based on molecular nanoparticles.

A major part of contemporary nanomaterials research is focused on metal and semiconductor nanoparticles, constituted of extended lattices of atoms or ions. Molecular nanoparticles assembled from small molecules through non-covalent interactions are relatively less explored but equally fascinating materials. Their unique and versatile characteristics have attracted considerable attention in recent years, establishing their identity and status as a novel class of nanomaterials. Optical characteristics of molecular nanoparticles capture the essence of their nanoscale features and form the basis of a variety of applications. This review describes the advances made in the field of fabrication of molecular nanoparticles, the wide spectrum of their optical and nonlinear optical characteristics and explorations of the potential applications that exploit their unique optical attributes.

Optically stimulated luminescence (OSL) dosimetry in medicine.

This paper reviews fundamental and practical aspects of optically stimulated luminescence (OSL) dosimetry pertaining to applications in medicine, having particularly in mind new researchers and medical physicists interested in gaining familiarity with the field. A basic phenomenological model for OSL is presented and the key processes affecting the outcome of an OSL measurement are discussed. Practical aspects discussed include stimulation modalities (continuous-wave OSL, pulsed OSL and linear modulation OSL), basic experimental setup, available OSL readers, optical fiber systems and basic properties of available OSL dosimeters. Finally, results from the recent literature on applications of OSL in radiotherapy, radiodiagnostics and heavy charged particle dosimetry are discussed in light of the theoretical and practical framework presented in this review. Open questions and future challenges in OSL dosimetry are highlighted as a guide to the research needed to further advance the field.